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Final Exam

  • Final Examination – Research on newly approved drug in 2023
  • Each student will be assigned a drug approved in 2023
  • Two parts – Written and Oral
    • Written research report – May 12 – for all the students
      • 2000 words minimum. No limit on maximum words
      • Includes figures, graphs, data and tables to support your writing (from research papers)
      • Include 3 references and more if you like (at the end of paper)
      • One of the references could be patent. If you include patent, then discuss it.
    • Oral Presentation of you work in the classroom – Week of 15, 16 and week 17
      • 10 to 12 minutes presentation
      • Walk us through your report about the drug
      • Slide deck is due 24 hrs before your presentation

Step 1

  • Drug information
  • Package insert
  • Web search: “PDF package insert Plavix”
  • Package insert is posted on LinkedIn

Identify three research papers, download and

submit PDF files online

  1. Definition, Classification and Diagnosis of Diabetes Mellitus. Petersmann A, Müller-Wieland D, Müller UA, Landgraf R, Nauck M, Freckmann G, Heinemann L, Schleicher E., Exp Clin Endocrinol Diabetes. 2019, 127 (S 01) p.S1-S7
  1. New Possibilities in the Therapeutic Approach to Alzheimer’s Disease. Doroszkiewicz J, Mroczko B. Int J Mol Sci. 2022, 23 (16), p8902. doi: 10.3390/ijms23168902.
  1. Ishino, T.; Palanki, M. S. S.; Violand, B.; Das, T.; Hodge, T.; Levin, N.; Parsons, E. Anti-diabetic compounds comprising fibroblast growth factor FGF21 covalently attached to combining site of antibody with prepared linker. WO 2012059873.

Final Exam – research paper and class room

presentation – What to present

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  • Introduction to diseases
    • Describe the diseases (symptoms and biology behind it)
    • Biological mechanism of diseases
    • Biological target for the drug
  • Patent information (google search, Espacenet.com )
  • Approach – small molecules vs. biologics
    • How was the drug was made (chemical vs. biological), structure, synthesis,
  • Scientific summary – clinical pharmacology
    • How the drug was absorbed, distributed, metabolized, eliminated (Pharmacokinetics)
    • What are the effects of drug on the body and on the diseases (Pharmacodynamics
  • Clinical studies (use package insert as guide)
  • Regulatory pathways
  • Recommended dosages, side effects, drug interactions
  • Information of use of drug in specific population, pediatric use, Geriatric use, ethnic use, pregnancy use, lactating mothers