Objective
Evaluate the impact of shigella infections in sub-Saharan Africa to guide vaccine development and enhance public health initiatives
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Research questions
- Which population group are mostly affected by shigellosis?
- How does antibiotic resistance affect shigellosis treatment
- What are the associated health consequences of shigellosis, including malnutrition and mortality rates.
Geographical and population focus
- Sub-Saharan Africa
- General population
Data sources
- Peer-review journal articles on shigella impact in sub-Saharan Africa
- Global and regional health agencies such as Centres for Disease Control and Prevention (CDC) and World Health Organisation (WHO)
- Other pertinent literature on the incidence, prevalence, and treatment of shigella disease in sub-Saharan Africa
Inclusion
- Studies conducted in rural and urban settings of sub-Saharan Africa
- Studies that provide empirical data on shigella
- Studies conducted from 2010 onward
Exclusion
- Shigella research outside sub-Saharan Africa
- Studies without quantitative data
- Non-peer- reviewed studies
Method of analysis
- Meta-analysis