Exploring The Impact of Shigella in Sub-Saharan Africa- A Comprehensive Systemic Review 

Objective 

Evaluate the impact of shigella infections in sub-Saharan Africa to guide vaccine development and enhance public health initiatives 

Research questions 

1. Which population group are mostly affected by shigellosis?
2. How does antibiotic resistance affect shigellosis treatment 
3. What are the associated health consequences of shigellosis, including malnutrition and mortality rates.

Geographical and population focus 

• Sub-Saharan Africa 
• General population 

Data sources 

• Peer-review journal articles on shigella impact in sub-Saharan Africa
• Global and regional health agencies such as Centres for Disease Control and Prevention (CDC) and World Health Organisation (WHO) 
• Other pertinent literature on the incidence, prevalence, and treatment of shigella disease in sub-Saharan Africa 

Inclusion 

• Studies conducted in rural and urban settings of sub-Saharan Africa 
• Studies that provide empirical data on shigella 
• Studies conducted from 2010 onward 

Exclusion 

• Shigella research outside sub-Saharan Africa
• Studies without quantitative data 
• Non-peer- reviewed studies

Method of analysis 

• Meta-analysis