Critical Appraisal of an Interventional Study: Advancing Evidence-Based Practice Through Rigorous Evaluation

This is the next step on the quest to answer your committee’s PICOT question. Use the article you selected in Literature Search and Article Selection assignment to complete this assignment. You may change articles if the article from Literature Search and Article Selection did not answer your questions, did not align closely enough with your PICOT or is a duplicate of another committee member.  This is an individual submission.

In this assignment you will:

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  1. Chart the information from the article into an appraisal template using the attached template. 
  2. Perform a quality assessment of the article by completing an appraisal template corresponding to research purpose.
  3. Include summary information regarding the quality of the article in the appraisal template.

Objective:

To gain experience critically appraising research and summarizing key information from a selected study.

Instructions:

Assignment Type: Written

Submission Requirements:

Limitations: None

Content Requirements:

  1. Template Selection: Select the correct template below that best matches the study type (purpose) from the article you selected. The options are hyperlinked and include: Interventional (Therapeutic) Download Interventional (Therapeutic), Prognostic Download Prognostic, Diagnostic Download Diagnostic, or Qualitative Download Qualitative.
  2. PICOT Question: State your clinical PICOT question on the top of the appraisal template.
  3. Level of Evidence: Determine the level of evidence for the study based on it study design.  Using the evidence pyramid from the library, identify what level your study design would be.  The top of the pyramid is a level 1 and the bottom of the pyramid is level 8.  Enter the corresponding number of your template.
  4. Data Charting: Accurately chart or extract each of the elements listed below from the article into the template in column 3. Details can be found on the respective templates. You may use N/A if the characteristic does not apply.
  1. Methods: Include the Study Design, Setting, Participants, Randomization
  2. Variables: Include the Type (Quantitative/Qualitatively); Variable Collection Method; Analysis Plan
  3. Results (include only those related to your PICOT question)

c.1 Quantitative: The table should include point estimates and confidence intervals. Use p-values to comment on statistical significance. In addition to the data points, include your interpretation of the results related to your PICOT question.

c.2 Qualitative: Include the findings from your study (e.g. themes)

d. Appraisal: The questions to conduct the appraisal are in the fourth column of the template. You will record your answers to those questions in column 5. The CEBM documents are references, which provides guidance on how to answer the questions on the template. They are hyperlinked and include CEBM: Interventional (Therapeutic) (PDF Attached)

  1. Bias: Assess for potential bias in the following areas: selection bias, knowledge of who received the intervention, gatekeeper, measurement bias, recall bias, information bias, loss to follow-up, and contamination bias.
  2. Validity, Reliability, & Applicability: At the end of the section for validity, write a summary including strengths and weakness of the design and an overall assessment. For reliability, you do not have to provide a summary.  For applicability to practice, answer the questions to determine if the study you reviewed is applicable to the clinical setting you described.
  3. Overall Style: Use of APA formatting and citations. Write your paper using scholarly writing principles related to grammar and spelling conventions.
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